Rootana Pure Mind Review: 16 Ingredients and Doses Checked

Pure Mind pros and cons

Pure Mind at a glance

What is Rootana Pure Mind?

Pure Mind is made by Rootana. Each three-capsule serving contains acetyl-L-carnitine (562.5 mg), lion's mane (412.5 mg), bacopa (225 mg at 50% bacosides), N-acetyl L-tyrosine (206 mg), citicoline (187.5 mg), L-theanine (150 mg), rhodiola (150 mg), phosphatidylserine (75 mg, from sunflower), pine bark extract (56 mg), saffron (22.5 mg), PQQ (7.5 mg), lutein (7.5 mg), zeaxanthin (1.5 mg) and activated forms of vitamin B6, folate and vitamin B12. The capsules are made from pullulan, and rice hull is the only other ingredient.

Take three capsules each morning with water. Rootana suggests four capsules for a stronger dose.

Pure Mind ingredients and doses

We grade Pure Mind on the same scale as every other product. The table compares each dose at the standard three-capsule serving with the research.

Bacopa monnieri (225 mg)

Bacopa is the most consistently studied herbal nootropic for memory. Twelve-week trials at 300 mg a day of an extract standardized to about 50% bacosides reported better memory consolidation in healthy adults and better delayed recall in people over 65, and a 2014 meta-analysis found faster attention and reaction times. It works slowly, and a 2025 trial found little effect on its main cognitive measures, so expect gradual, modest change.

At 225 mg, the dose is respectable but short of the 300 mg a day of extract standardized to about 50% bacosides (about 150 mg of bacosides) used in studies. Standardized to 50% bacosides, it delivers about 112 mg of bacosides against roughly 150 mg in the main trials.

Citicoline (187.5 mg)

Studies have used 250 to 500 mg a day. The clearest results are modest improvements in memory and attention, mostly seen over several weeks of daily use and in older adults.

Pure Mind includes 187.5 mg. That is a reasonable amount, though below the 250 to 500 mg a day that most trials used.

L-theanine (150 mg)

Studies have used 100 to 400 mg a day, most often 200 mg. On its own L-theanine eases stress and supports sleep quality; with caffeine it improves accuracy and attention more than caffeine does by itself.

Pure Mind's 150 mg sits within the 100 to 400 mg, most often 200 mg used in the trials.

Rhodiola rosea (150 mg)

Night-shift doctors taking 170 mg of rhodiola a day for two weeks performed better on mental tasks, and adults with stress-related fatigue taking 576 mg a day for four weeks reported less fatigue and better concentration. Extracts standardized to 3% rosavins and 1% salidroside match those used in research.

Pure Mind includes 150 mg. That is a reasonable amount, though below the 170 to 600 mg a day of standardized extract that most trials used.

Phosphatidylserine (75 mg)

Phosphatidylserine has been studied at 100 to 300 mg a day, mainly in older adults with memory complaints, where it produced modest improvements over several months.

Pure Mind includes 75 mg. That is a reasonable amount, though below the 100 to 300 mg a day that most trials used.

Saffron extract (22.5 mg)

In a four-week trial, healthy adults with low mood taking 28 mg of a saffron extract a day reported better mood and less stress than the placebo group. Most mood research has used 28 to 30 mg a day.

Pure Mind includes 22.5 mg. That is a reasonable amount, though below the 28 to 30 mg a day that most trials used.

Three capsules or four?

At three capsules, Pure Mind's 150 mg of L-theanine is within the researched range, and its bacopa, citicoline, rhodiola, phosphatidylserine, saffron, lutein and zeaxanthin are at roughly three quarters of the amounts used in studies. At four capsules, those become 300 mg of bacopa, 250 mg of citicoline, 200 mg each of L-theanine and rhodiola, 100 mg of phosphatidylserine and 30 mg of saffron, which match the research doses.

Four capsules a day means a bottle lasts 21 days instead of 28, so the cost rises from about $1.43 to $1.90 a day at the single-bottle price. If budget matters most, start with three. If you want the full research doses, take four.

Pure Mind vs ThinkEase

Pure Mind and ThinkEase share the same 16 ingredients in the same proportions. ThinkEase's standard four-capsule serving delivers the full research doses and comes with a 100-day money-back guarantee, at $74.99 a bottle or $44.99 on the five-month pack. Pure Mind's standard serving is three capsules, its bottles cost less, and its returns policy covers unopened bottles only.

Choose ThinkEase if you want the full doses in the standard serving and the longer guarantee. Choose Pure Mind if price matters most or you prefer a three-capsule routine. See our ThinkEase review.

What results to expect

L-theanine has shown effects within hours of a single dose in studies, so calmer, steadier focus is the first change to look for. Rhodiola's fatigue trials ran for two to four weeks, while bacopa's memory benefits build over eight to twelve weeks of daily use, so give Pure Mind at least two months before judging it. Sleep, exercise and stress have a bigger effect on how sharp you feel than any supplement.

Pure Mind side effects

Pure Mind is caffeine-free and suits most people. Bacopa can cause mild stomach upset, so take it with breakfast, and rhodiola can feel mildly stimulating, so take it in the morning. Rootana advises against it for anyone under 18 or pregnant or nursing, and recommends checking with your doctor first if you take medication, particularly anything affecting mood, blood pressure or blood clotting.

Pure Mind price and returns

One bottle of 84 capsules costs $39.99 and lasts 28 days at three capsules a day, about $1.43 a day. Two bottles cost $79.98, and the 3 + 1 free pack costs $119.97 for four bottles, $29.99 a bottle or about $1.07 a day. Subscribe and Save takes 15% off every order.

Unopened bottles can be returned within 30 days of delivery in the US and Canada, or 14 days in the UK and EU. Shipping is free to the US and UK on orders over $80 or £50.

Pure Mind vs ThinkEase, MindVitality and Mind Lab Pro

Our scores

How we score: formula and dosing 35%, ingredient evidence 25%, label transparency 20%, value and terms 20%. Read our rating method.

Why we recommend Rootana Pure Mind

Highest rated nootropic under $40

Why we recommend Rootana Pure Mind

• The same 16 ingredients as our top-rated nootropic, from $29.99 a bottle
• Bacopa at 50% bacosides, citicoline, L-theanine, rhodiola, phosphatidylserine and saffron in one daily routine
• Caffeine-free, vegan and fully disclosed, with no proprietary blends
• Four capsules a day reaches the full research doses when you want them

Learn more at rootana.com →